The meaning of SAFE is free from harm or risk : unhurt. How to use safe in a sentence. Usage of Safe: Usage Guide. SAFe 6 is an update to the SAFe Framework to help organizations become Lean Enterprise and achieve Business Agility. Learn more and see FAQs about 6. The scaled Agile framework (SAFe) provides structured guidance for implementing Agile practices across large organizations. SAFe emphasizes alignment, built-in quality, transparency, and program execution, with principles rooted in lean and systems thinking. Shop for safes at Amazon.com. Eligible for free shipping and free returns. A safe will protect your valuables from theft. Though you might want to put your irreplaceables in a bank safety deposit box, a home safe can give you peace of mind for documents and other valuables you want to keep at home. Keep people safe, reduce risk and drive efficiency with industrial-strength guardrails and barriers that flex upon impact, absorb vehicle energy, and then reform for continued protection. SAFE Credit Union provides credit cards, mortgages, commercial lending, auto loans, investing & retirement planning, checking and business banking.